Pseudomonas aeruginosa PAO1, PA3779

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3779
Name
Replicon chromosome
Genomic location 4237693 - 4238733 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs
CommentStructural similarity to 4P47 (TRAP periplasmic solute binding protein from Ochrobactrum anthropi, root-mean-square deviation: 1.2 angstroms). Sequence similarity to 4N8G (98%/63,99%) (DAL). Final predicted ligand: dipeptide (PMID: 31631799)

Cross-References

RefSeq NP_252468.1
GI 15598974
Affymetrix PA3779_at
Entrez 879148
GenBank AAG07166.1
INSDC AAG07166.1
NCBI Locus Tag PA3779
protein_id(GenBank) gb|AAG07166.1|AE004797_1|gnl|PseudoCAP|PA3779
TIGR NTL03PA03779
UniParc UPI00000C5B0A
UniProtKB Acc Q9HXL6
UniProtKB ID Q9HXL6_PSEAE
UniRef100 UniRef100_Q9HXL6
UniRef50 UniRef50_Q9HXL6
UniRef90 UniRef90_Q9HXL6

Product

Feature Type CDS
Coding Frame 1
Product Name
putative periplasmic substrate binding protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -5.03
Kyte-Doolittle Hydrophobicity Value -0.180
Molecular Weight (kDa) 37.7
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 245 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000851 (1038 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3779

Human Homologs

References

Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
Uncovering the structure and function of <i>Pseudomonas aeruginosa</i> periplasmic proteins by an <i>in silico</i> approach.
Caprari S, Brandi V, Pasquadibisceglie A, Polticelli F
J Biomol Struct Dyn 2019 Oct 30;:1-13
PubMed ID: 31631799