Pseudomonas aeruginosa UCBPP-PA14, PA14_00960 (tssJ1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_00960
Name
tssJ1
Replicon chromosome
Genomic location 95402 - 95866 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788236.1
GI 116053799
Entrez 4380425
INSDC ABJ15035.1
NCBI Locus Tag PA14_00960
UniParc UPI00000C4F21
UniProtKB Acc Q02V00
UniProtKB ID Q02V00_PSEAB
UniRef100 UniRef100_W0YJI0
UniRef50 UniRef50_A6UXL2
UniRef90 UniRef90_A6UXL2

Product

Feature Type CDS
Coding Frame 1
Product Name
TssJ1
Product Name Confidence: Class 1
Synonyms lipoprotein
Evidence for Translation
Charge (pH 7) -0.56
Kyte-Doolittle Hydrophobicity Value -0.173
Molecular Weight (kDa) 16.9
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3ZHN TOXIN 12/22/12 Crystal structure of the T6SS lipoprotein TssJ1 from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.4 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 77 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000079 (812 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00960
Search term: tssJ1
Search term: TssJ1

Human Homologs

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999