Pseudomonas aeruginosa UCBPP-PA14, PA14_48530

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_48530
Name
Replicon chromosome
Genomic location 4314228 - 4316084 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_792029.1
GI 116049169
Entrez 4380165
NCBI Locus Tag PA14_48530

Product

Feature Type CDS
Coding Frame 1
Product Name
AMP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7) 2.44
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 67.6
Isoelectric Point (pI) 7.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4DG8 LIGASE 01/25/12 Structure of PA1221, an NRPS protein containing adenylation and PCP domains Pseudomonas aeruginosa 2.15 X-RAY DIFFRACTION 98.4
4DG9 LIGASE/Inhibitor 01/25/12 Structure of holo-PA1221, an NRPS protein containing adenylation and PCP domains bound to vinylsulfonamide inhibitor Pseudomonas aeruginosa 2.55 X-RAY DIFFRACTION 98.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 497 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001177 (302 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_48530

Human Homologs

References

No references are associated with this feature.