Pseudomonas aeruginosa UCBPP-PA14, PA14_50680 (shaA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_50680
Name	shaA
Replicon	chromosome
Genomic location	4502114 - 4502461 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq	YP_792210.1
GI	116048988
Entrez	4384768
INSDC	ABJ10224.1
NCBI Locus Tag	PA14_50680
UniParc	UPI00003965BF
UniProtKB Acc	Q02IM6
UniProtKB ID	Q02IM6_PSEAB
UniRef100	UniRef100_Q02IM6
UniRef50	UniRef50_Q02IM6
UniRef90	UniRef90_Q02IM6

Product

Feature Type	CDS
Coding Frame	1
Product Name	ShaA Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	2.46
Kyte-Doolittle Hydrophobicity Value	0.687
Molecular Weight (kDa)	12.6
Isoelectric Point (pI)	9.63

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 219 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001021 (414 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_50680 Search term: shaA Search term: ShaA

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis. Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T J Bacteriol 2005 Aug;187(15):5242-8 PubMed ID: 16030218