Pseudomonas aeruginosa UCBPP-PA14, PA14_50720 (shaE)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_50720
Name	shaE
Replicon	chromosome
Genomic location	4504729 - 4505067 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq	YP_792214.1
GI	116048984
Entrez	4384764
INSDC	ABJ10220.1
NCBI Locus Tag	PA14_50720
UniParc	UPI00000C5229
UniProtKB Acc	Q02IM2
UniProtKB ID	Q02IM2_PSEAB
UniRef100	UniRef100_W0YPT3
UniRef50	UniRef50_Q52980
UniRef90	UniRef90_A6V9E1

Product

Feature Type	CDS
Coding Frame	1
Product Name	ShaE Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	-3.78
Kyte-Doolittle Hydrophobicity Value	0.821
Molecular Weight (kDa)	11.7
Isoelectric Point (pI)	4.40

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 238 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001017 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_50720 Search term: shaE Search term: ShaE

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis. Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T J Bacteriol 2005 Aug;187(15):5242-8 PubMed ID: 16030218