Pseudomonas aeruginosa UCBPP-PA14, PA14_00050 (gyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_00050
Name
gyrB
Replicon chromosome
Genomic location 4275 - 6695 (+ strand)

Cross-References

RefSeq YP_788159.1
GI 116053724
Entrez 4384102
INSDC ABJ14960.1
NCBI Locus Tag PA14_00050
UniParc UPI00000C4EE1
UniProtKB Acc Q02V77
UniProtKB ID Q02V77_PSEAB
UniRef100 UniRef100_Q9I7C2
UniRef50 UniRef50_P13364
UniRef90 UniRef90_Q9I7C2

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA gyrase subunit B
Evidence for Translation
Charge (pH 7) -15.76
Kyte-Doolittle Hydrophobicity Value -0.411
Molecular Weight (kDa) 90.2
Isoelectric Point (pI) 5.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
Mycobacterium tuberculosis gyrB mutant conferring resistance to fluoroquinolone Point mutation in Mycobacterium tuberculosis gyrB resulting in fluoroquinolone resistance ARO:3003459 protein variant model V340L Strict 0.0 0.485866 1.1.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000004 (561 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00050
Search term: gyrB

Human Homologs

Ensembl 86, assembly GRCh38.p7
topoisomerase (DNA) II alpha [Source:HGNC Symbol;Acc:HGNC:11989]
E-value: 1.8e-30
Percent Identity: 23.8

References

No references are associated with this feature.