Pseudomonas aeruginosa UCBPP-PA14, PA14_00990 (tssA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_00990
Name
tssA1
Replicon chromosome
Genomic location 97777 - 98811 (+ strand)
Transposon Mutants in orthologs 7 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788239.1
GI 116053802
Entrez 4380428
INSDC ABJ15038.1
NCBI Locus Tag PA14_00990
UniParc UPI0000396C17
UniProtKB Acc Q02UZ7
UniProtKB ID Q02UZ7_PSEAB
UniRef100 UniRef100_Q02UZ7
UniRef50 UniRef50_Q4K3N9
UniRef90 UniRef90_Q9I750

Product

Feature Type CDS
Coding Frame 1
Product Name
TssA1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -22.53
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 4.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 81 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000081 (1226 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00990
Search term: tssA1
Search term: TssA1

References

TssA forms a gp6-like ring attached to the type VI secretion sheath.
Planamente S, Salih O, Manoli E, Albesa-Jové D, Freemont PS, Filloux A
EMBO J. 2016 Aug;35(15):1613-27
PubMed ID: 27288401
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999