Pseudomonas aeruginosa UCBPP-PA14, PA14_05230

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_05230
Name
Replicon chromosome
Genomic location 456745 - 457929 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_788574.1
GI 116054131
Entrez 4383790
INSDC ABJ15367.1
NCBI Locus Tag PA14_05230
UniParc UPI0000396D45
UniProtKB Acc Q02U12
UniProtKB ID Q02U12_PSEAB
UniRef100 UniRef100_A0A0C6E8Z8
UniRef50 UniRef50_Q8VCN5
UniRef90 UniRef90_A0A0A8RC28

Product

Feature Type CDS
Coding Frame 1
Product Name
cystathionine gamma-lyase
Synonyms
Evidence for Translation
Charge (pH 7) -2.75
Kyte-Doolittle Hydrophobicity Value -0.047
Molecular Weight (kDa) 42.8
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7BA4 CYTOSOLIC PROTEIN 12/15/20 Structure of Cystathionine gamma-lyase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000391 (846 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_05230

Human Homologs

Ensembl 110, assembly GRCh38.p14
cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]
E-value: 8.4e-103
Percent Identity: 52.2

References

No references are associated with this feature.