Pseudomonas aeruginosa UCBPP-PA14, PA14_24610

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_24610
Name
Replicon	chromosome
Genomic location	2151239 - 2152240 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	14 transposon mutants in orthologs

Cross-References

RefSeq	YP_790118.1
GI	116051053
Entrez	4381077
INSDC	ABJ12289.1
NCBI Locus Tag	PA14_24610
UniParc	UPI0000395F94
UniProtKB Acc	Q02PL8
UniProtKB ID	Q02PL8_PSEAB
UniRef100	UniRef100_A0A080VQ00
UniRef50	UniRef50_M5CPN2
UniRef90	UniRef90_Q9HZF5

Product

Feature Type	CDS
Coding Frame	1
Product Name	hydrolytic enzyme
Synonyms
Evidence for Translation
Charge (pH 7)	4.55
Kyte-Doolittle Hydrophobicity Value	-0.246
Molecular Weight (kDa)	37.3
Isoelectric Point (pI)	8.53

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4F0J	HYDROLASE	05/04/12	Crystal structure of a probable hydrolytic enzyme (PA3053) from Pseudomonas aeruginosa PAO1 at 1.50 A resolution	Pseudomonas aeruginosa	1.5	X-RAY DIFFRACTION	99.7

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 454 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000798 (2691 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_24610 Search term: hydrolytic enzyme

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000369843 epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] E-value: 3.4e-12 Percent Identity: 34.1
Ensembl 110, assembly GRCh38.p14	ENSP00000430302 epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] E-value: 3.4e-12 Percent Identity: 34.1
Ensembl 110, assembly GRCh38.p14	ENSP00000430269 epoxide hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3402] E-value: 3.4e-12 Percent Identity: 34.1

References