Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_25660
|
Name |
fabG
|
Replicon | chromosome |
Genomic location | 2243222 - 2243965 (+ strand) |
RefSeq | YP_790206.1 |
GI | 116050969 |
EC Number | 1.1.1.100 |
Entrez | 4384348 |
INSDC | ABJ12205.1 |
NCBI Locus Tag | PA14_25660 |
UniParc | UPI000012A462 |
UniProtKB Acc | Q02PD0 |
UniProtKB ID | Q02PD0_PSEAB |
UniRef100 | UniRef100_O54438 |
UniRef50 | UniRef50_P0AEK2 |
UniRef90 | UniRef90_O54438 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
3-ketoacyl-ACP reductase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -0.52 |
Kyte-Doolittle Hydrophobicity Value | 0.176 |
Molecular Weight (kDa) | 25.6 |
Isoelectric Point (pI) | 6.56 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4BO7 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(2,3-dihydro-1H-inden- 5-yl)tetrazolo(1,5-b)pyridazin-6-amine at 2.6A resolution | PSEUDOMONAS AERUGINOSA | 2.6 | X-RAY DIFFRACTION | 100.0 |
4BO6 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2,3-dihydroindol-1-yl-(2- thiophen-3-yl-1,3-thiazol-4-yl)methanone at 2.8A resolution | PSEUDOMONAS AERUGINOSA | 2.8 | X-RAY DIFFRACTION | 100.0 |
4BO2 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(1-ethylbenzimidazol-2- yl)-3-(2-methoxyphenyl)urea at 1.9A resolution | PSEUDOMONAS AERUGINOSA | 1.9 | X-RAY DIFFRACTION | 100.0 |
4BO0 | OXIDOREDUCTASE | 05/17/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution | PSEUDOMONAS AERUGINOSA | 2.4 | X-RAY DIFFRACTION | 100.0 |
4BO1 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(4-chloro-2,5- dimethoxyphenyl)quinoline-8-carboxamide at 2.2A resolution | PSEUDOMONAS AERUGINOSA | 2.2 | X-RAY DIFFRACTION | 100.0 |
4BO3 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-(3-(trifluoromethyl) anilino)pyridine-3-sulfonamide at 2.5A resolution | PSEUDOMONAS AERUGINOSA | 2.5 | X-RAY DIFFRACTION | 100.0 |
4BO9 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 5-(2-(furan-2-ylmethoxy) phenyl)-2-phenyltetrazole at 2.9A resolution | PSEUDOMONAS AERUGINOSA | 2.9 | X-RAY DIFFRACTION | 100.0 |
4BO8 | OXIDOREDUCTASE | 05/18/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(2-amino-4- phenylimidazol-1-yl)-3-(2-fluorophenyl)urea at 2.7A resolution | PSEUDOMONAS AERUGINOSA | 2.7 | X-RAY DIFFRACTION | 100.0 |
4BNY | OXIDOREDUCTASE | 05/17/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d) pyrimidin-4-yl)morpholine at 1.8A resolution | PSEUDOMONAS AERUGINOSA | 1.8 | X-RAY DIFFRACTION | 100.0 |
4BNZ | OXIDOREDUCTASE | 05/17/13 | Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-methyl-N-phenylindole- 3-carboxamide at 2.5A resolution | PSEUDOMONAS AERUGINOSA | 2.5 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002615 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_25660
Search term: fabG
Search term: 3-ketoacyl-ACP reductase
|
Ensembl
110, assembly
GRCh38.p14
|
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value:
4.4e-41
Percent Identity:
42.7
|