Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_25740
|
Name |
tmk
|
Replicon | chromosome |
Genomic location | 2247669 - 2248301 (+ strand) |
RefSeq | YP_790211.1 |
GI | 116050964 |
Entrez | 4384343 |
INSDC | ABJ12200.1 |
NCBI Locus Tag | PA14_25740 |
UniParc | UPI0000395F57 |
UniProtKB Acc | Q02PC5 |
UniProtKB ID | KTHY_PSEAB |
UniRef100 | UniRef100_Q02PC5 |
UniRef50 | UniRef50_B7V167 |
UniRef90 | UniRef90_B7V167 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
thymidylate kinase
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -4.79 |
Kyte-Doolittle Hydrophobicity Value | -0.183 |
Molecular Weight (kDa) | 23.1 |
Isoelectric Point (pI) | 4.86 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4GMD | Transferase/Inhibitor | 08/15/12 | The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate | Pseudomonas aeruginosa | 1.98 | X-RAY DIFFRACTION | 98.1 |
4E5U | TRANSFERASE | 03/14/12 | The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with thymidine monophosphate. | Pseudomonas aeruginosa | 1.812 | X-RAY DIFFRACTION | 98.1 |
4ESH | TRANSFERASE | 04/23/12 | The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with deoxythymidine. | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 98.1 |
4EDH | TRANSFERASE | 03/27/12 | The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with ADP,TMP and Mg. | Pseudomonas aeruginosa PAO1 | 1.32 | X-RAY DIFFRACTION | 98.1 |
3UWO | TRANSFERASE/TRANSFERASE INHIBITOR | 12/02/11 | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | Pseudomonas aeruginosa | 1.7 | X-RAY DIFFRACTION | 98.1 |
3UWK | TRANSFERASE/TRANSFERASE INHIBITOR | 12/02/11 | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | Pseudomonas aeruginosa | 1.91 | X-RAY DIFFRACTION | 98.1 |
3UXM | TRANSFERASE/TRANSFERASE INHIBITOR | 12/05/11 | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 98.1 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 569 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002620 (530 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_25740
Search term: tmk
Search term: thymidylate kinase
|