Pseudomonas aeruginosa UCBPP-PA14, PA14_25800

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_25800
Name
Replicon chromosome
Genomic location 2251906 - 2252544 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_790216.1
GI 116050959
Entrez 4384338
INSDC ABJ12195.1
NCBI Locus Tag PA14_25800
UniParc UPI00000C58A7
UniProtKB Acc Q02PC0
UniProtKB ID Q02PC0_PSEAB
UniRef100 UniRef100_W0YSW9
UniRef50 UniRef50_G8Q174
UniRef90 UniRef90_M4X208

Product

Feature Type CDS
Coding Frame 1
Product Name
TetR family transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) 0.66
Kyte-Doolittle Hydrophobicity Value -0.553
Molecular Weight (kDa) 25.0
Isoelectric Point (pI) 7.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7W2O DNA BINDING PROTEIN 11/24/21 Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the wide conformation Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.21 X-RAY DIFFRACTION 100.0
7Y0Y TRANSCRIPTION 06/06/22 Crystal structure of Pseudomonas aeruginosa PvrA (SeMet) Pseudomonas aeruginosa PA14 2.09 X-RAY DIFFRACTION 100.0
7XAQ TRANSCRIPTION 03/18/22 Cryo-EM structure of PvrA-DNA complex Pseudomonas aeruginosa PAO1 3.59 ELECTRON MICROSCOPY 100.0
8HJB TRANSCRIPTION 11/23/22 Crystal structure of Pseudomonas aeruginosa PvrA with coenzyme A Pseudomonas aeruginosa PA14 2.65 X-RAY DIFFRACTION 100.0
7Y0Z TRANSCRIPTION 06/06/22 Crystal structure of Pseudomonas aeruginosa PvrA Pseudomonas aeruginosa PA14 2.3 X-RAY DIFFRACTION 100.0
7W2Q DNA BINDING PROTEIN 11/24/21 Crystal structure of Pseudomonas aeruginosa transcriptional regulator PvrA in the narrow conformation Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002624 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_25800

Human Homologs

References

No references are associated with this feature.