Pseudomonas aeruginosa UCBPP-PA14, PA14_29350 (pfeA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_29350
Name
pfeA
Replicon chromosome
Genomic location 2539430 - 2541670 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 27 transposon mutants in orthologs

Cross-References

RefSeq YP_790507.1
GI 116050673
Entrez 4380717
INSDC ABJ11909.1
NCBI Locus Tag PA14_29350
UniParc UPI0000395E84
UniProtKB Acc Q02NH9
UniProtKB ID Q02NH9_PSEAB
UniRef100 UniRef100_Q02NH9
UniRef50 UniRef50_P05825
UniRef90 UniRef90_Q05098

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane receptor FepA
Synonyms
Evidence for Translation
Charge (pH 7) -9.70
Kyte-Doolittle Hydrophobicity Value -0.562
Molecular Weight (kDa) 81.0
Isoelectric Point (pI) 5.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6R1F MEMBRANE PROTEIN 03/14/19 Crystal structure of the ferric enterobactin receptor mutant R480A from Pseudomonas aeruginosa (PfeA) in complex with enterobactin Pseudomonas aeruginosa PAO1 3.11 X-RAY DIFFRACTION 99.7
7OBW MEMBRANE PROTEIN 04/23/21 Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with TCV-L6 Pseudomonas aeruginosa PAO1 2.66 X-RAY DIFFRACTION 99.9
5M9B MEMBRANE PROTEIN 11/01/16 Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 2.12 X-RAY DIFFRACTION 99.9
5NR2 MEMBRANE PROTEIN 04/21/17 Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with azotochelin Pseudomonas aeruginosa 2.78 X-RAY DIFFRACTION 99.9
6I2J MEMBRANE PROTEIN 11/01/18 Crystal structure of the ferric enterobactin receptor mutant (Q482A) from Pseudomonas aeruginosa (PfeA) in complex with enterobactin Pseudomonas aeruginosa PAO1 2.96 X-RAY DIFFRACTION 99.7
6YY5 MEMBRANE PROTEIN 05/04/20 Crystal structure of the ferric enterobactin receptor (PfeA) in complex with TCV_L5 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.717 X-RAY DIFFRACTION 99.9
5NC4 MEMBRANE PROTEIN 03/03/17 Crystal structure of the ferric enterobactin receptor (PfeA) in complex with protochelin from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.8 X-RAY DIFFRACTION 99.9
5NC3 MEMBRANE PROTEIN 03/03/17 Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with the tris-catechol vector Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.57 X-RAY DIFFRACTION 99.9
5MZS MEMBRANE PROTEIN 02/01/17 Crystal structure of the ferric enterobactin receptor (PfeA) mutant (R480A_Q482A) from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.67 X-RAY DIFFRACTION 99.6
6Q5E MEMBRANE PROTEIN 12/07/18 Crystal structure of the ferric enterobactin receptor from Pseudomonas aeruginosa (PfeA) in complex with enterobactin Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.7 X-RAY DIFFRACTION 99.9
6Y47 MEMBRANE PROTEIN 02/19/20 Crystal structure of the ferric enterobactin receptor (PfeA) in complex with BCV-L5 Pseudomonas aeruginosa PAO1 3.04 X-RAY DIFFRACTION 99.9
5OUT MEMBRANE PROTEIN 08/24/17 CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) MUTANT (G324V) FROM PSEUDOMONAS AERUGINOSA Pseudomonas aeruginosa PAO1 2.9 X-RAY DIFFRACTION 99.7
6Z33 MEMBRANE PROTEIN 05/19/20 Crystal structure of the ferric enterobactin receptor (PfeA) in complex with BCV Pseudomonas aeruginosa PAO1 2.711 X-RAY DIFFRACTION 99.9
6Z2N MEMBRANE PROTEIN 05/18/20 Crystal structure of the ferric enterobactin receptor (PfeA) in complex with BCV-L6 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.029 X-RAY DIFFRACTION 99.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 329 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000897 (3061 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_29350
Search term: pfeA

Human Homologs

References

No references are associated with this feature.