Pseudomonas aeruginosa UCBPP-PA14, PA14_30050

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_30050
Name
Replicon chromosome
Genomic location 2602558 - 2604153 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_790560.1
GI 116050621
EC Number 4.1.3.1
Entrez 4380665
INSDC ABJ11857.1
NCBI Locus Tag PA14_30050
UniParc UPI0000395E5E
UniProtKB Acc Q02NC6
UniProtKB ID Q02NC6_PSEAB
UniRef100 UniRef100_W0YT58
UniRef50 UniRef50_O50078
UniRef90 UniRef90_Q9I0K4

Product

Feature Type CDS
Coding Frame 1
Product Name
isocitrate lyase
Synonyms
Evidence for Translation
Charge (pH 7) -8.85
Kyte-Doolittle Hydrophobicity Value -0.312
Molecular Weight (kDa) 58.9
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6G1O LYASE 03/21/18 Structure of Pseudomonas aeruginosa Isocitrate Lyase, ICL Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.882 X-RAY DIFFRACTION 99.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002919 (354 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_30050
Search term: isocitrate lyase

Human Homologs

References

No references are associated with this feature.