Pseudomonas aeruginosa UCBPP-PA14, PA14_60730

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_60730
Name
Replicon chromosome
Genomic location 5411518 - 5412909 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_793048.1
GI 116052731
Entrez 4385721
INSDC ABJ13967.1
NCBI Locus Tag PA14_60730
UniParc UPI0000E44C0D
UniProtKB Acc Q02G88
UniProtKB ID Q02G88_PSEAB
UniRef100 UniRef100_B7V0D3
UniRef50 UniRef50_E2XT92
UniRef90 UniRef90_B7V0D3

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane protein
Synonyms
Evidence for Translation
Charge (pH 7) -2.59
Kyte-Doolittle Hydrophobicity Value -0.251
Molecular Weight (kDa) 49.7
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3DWO MEMBRANE PROTEIN 07/22/08 Crystal structure of a Pseudomonas aeruginosa FadL homologue Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 99.8

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
(Hydroxyethyloxy)Tri(Ethyloxy)Octane DB04233 DrugBank 5.1.4 Q9HVJ6 Probable outer membrane protein 99.8 463 5.0e-275

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 184 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004247 (347 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_60730

Human Homologs

References

No references are associated with this feature.