Pseudomonas aeruginosa UCBPP-PA14, PA14_01140 (tse6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_01140
Name
tse6
Replicon chromosome
Genomic location 111195 - 112514 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 13 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788251.1
GI 116053814
Entrez 4383512
NCBI Locus Tag PA14_01140

Product

Feature Type CDS
Coding Frame 1
Product Name
Tse6
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 7.14
Kyte-Doolittle Hydrophobicity Value 0.092
Molecular Weight (kDa) 45114.7
Isoelectric Point (pI) 9.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 23 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000092 (1695 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01140
Search term: tse6
Search term: Tse6

References

An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
Whitney JC, Quentin D, Sawai S, LeRoux M, Harding BN, Ledvina HE, Tran BQ, Robinson H, Goo YA, Goodlett DR, Raunser S, Mougous JD
Cell 2015 Oct;163(3):607-19
PubMed ID: 26456113
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999