Pseudomonas aeruginosa UCBPP-PA14, PA14_25910

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_25910
Name
Replicon	chromosome
Genomic location	2260023 - 2260970 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	14 transposon mutants in orthologs

Cross-References

RefSeq	YP_790224.1
GI	116050951
Entrez	4384330
INSDC	ABJ12187.1
NCBI Locus Tag	PA14_25910
UniParc	UPI0000395F51
UniProtKB Acc	Q02PB2
UniProtKB ID	Q02PB2_PSEAB
UniRef100	UniRef100_W1MJU3
UniRef50	UniRef50_F6AH52
UniRef90	UniRef90_Q9KJG6

Product

Feature Type	CDS
Coding Frame	1
Product Name	lipase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.10
Kyte-Doolittle Hydrophobicity Value	-0.037
Molecular Weight (kDa)	34.8
Isoelectric Point (pI)	6.52

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6I8W	HYDROLASE	11/21/18	Crystal structure of a membrane phospholipase A, a novel bacterial virulence factor	Pseudomonas aeruginosa	2	X-RAY DIFFRACTION	99.7

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 503 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000798 (2691 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_25910 Search term: lipase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000410323 epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760] E-value: 9.0e-15 Percent Identity: 24.8
Ensembl 110, assembly GRCh38.p14	ENSP00000221730 epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760] E-value: 9.0e-15 Percent Identity: 24.8
Ensembl 110, assembly GRCh38.p14	ENSP00000469345 epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760] E-value: 9.0e-15 Percent Identity: 24.8

References