Pseudomonas aeruginosa UCBPP-PA14, PA14_38440 (gnyD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_38440
Name
gnyD
Replicon chromosome
Genomic location 3427846 - 3429009 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791224.1
GI 116049966
Entrez 4380300
INSDC ABJ11202.1
NCBI Locus Tag PA14_38440
UniParc UPI000045D24B
UniProtKB Acc Q02LG2
UniProtKB ID Q02LG2_PSEAB
UniRef100 UniRef100_Q02LG2
UniRef50 UniRef50_Q92VK1
UniRef90 UniRef90_Q02LG2

Product

Feature Type CDS
Coding Frame 1
Product Name
citronelloyl-CoA dehydrogenase, GnyD
Synonyms
Evidence for Translation
Charge (pH 7) -5.67
Kyte-Doolittle Hydrophobicity Value -0.138
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 5.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 485 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003424 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_38440
Search term: gnyD

Human Homologs

Ensembl 110, assembly GRCh38.p14
isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186]
E-value: 1.0e-137
Percent Identity: 64.0
Ensembl 110, assembly GRCh38.p14
isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186]
E-value: 1.0e-137
Percent Identity: 64.0

References

No references are associated with this feature.