Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_51430
|
Name |
pqsA
|
Replicon | chromosome |
Genomic location | 4569916 - 4571469 (- strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | YP_792275.1 |
GI | 116048924 |
Entrez | 4379980 |
INSDC | ABJ10160.1 |
NCBI Locus Tag | PA14_51430 |
UniParc | UPI0000396581 |
UniProtKB Acc | Q02IG1 |
UniProtKB ID | Q02IG1_PSEAB |
UniRef100 | UniRef100_S0IZ18 |
UniRef50 | UniRef50_Q9I4X3 |
UniRef90 | UniRef90_Q9I4X3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
PqsA
|
Synonyms |
coenzyme A ligase |
Evidence for Translation | |
Charge (pH 7) | -6.98 |
Kyte-Doolittle Hydrophobicity Value | -0.054 |
Molecular Weight (kDa) | 56.5 |
Isoelectric Point (pI) | 6.15 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5OE3 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1) | Pseudomonas aeruginosa PAO1 | 1.43 | X-RAY DIFFRACTION | 99.0 |
5OE6 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with 6-fluoroanthraniloyl-AMP (crystal form 1) | Pseudomonas aeruginosa PAO1 | 1.67 | X-RAY DIFFRACTION | 99.0 |
5OE5 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 3) | Pseudomonas aeruginosa PAO1 | 1.74 | X-RAY DIFFRACTION | 99.0 |
5OE4 | LIGASE | 07/07/17 | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 2) | Pseudomonas aeruginosa PAO1 | 1.904 | X-RAY DIFFRACTION | 99.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000959 (296 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_51430
Search term: pqsA
Search term: PqsA
|
Ensembl
110, assembly
GRCh38.p14
|
acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]
E-value:
1.4e-25
Percent Identity:
24.7
|
Ensembl
110, assembly
GRCh38.p14
|
acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]
E-value:
1.4e-25
Percent Identity:
24.7
|
PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis.
Lépine F, Dekimpe V, Lesic B, Milot S, Lesimple A, Mamer OA, Rahme LG, Déziel E
Biol Chem 2007 Aug;388(8):839-45
PubMed ID: 17655503
|