Pseudomonas aeruginosa UCBPP-PA14, PA14_59800 (pvrS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_59800
Name
pvrS
Synonym: RL036
Replicon chromosome
Genomic location 5324826 - 5327621 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792968.1
GI 116052653
Entrez 4385474
INSDC ABJ13889.1
NCBI Locus Tag PA14_59800
UniParc UPI0000E44BFB
UniProtKB Acc Q02GG8
UniProtKB ID Q02GG8_PSEAB
UniRef100 UniRef100_Q02GG8
UniRef50 UniRef50_A6V5P0
UniRef90 UniRef90_Q02GG8

Product

Feature Type CDS
Coding Frame 1
Product Name
PvrS
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -17.16
Kyte-Doolittle Hydrophobicity Value 0.089
Molecular Weight (kDa) 101.6
Isoelectric Point (pI) 5.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Mus musculus
Notes
Infection model Mouse thermal injury model.
Reference 14983043
Source 2
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Arabidopsis thaliana
Notes
Infection model Arabidopsis leaf infiltration model
Reference 14983043

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG014999 (89 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_59800
Search term: pvrS
Search term: PvrS

Human Homologs

References

The pathogenicity island encoded PvrSR/RcsCB regulatory network controls biofilm formation and dispersal in Pseudomonas aeruginosa PA14.
Mikkelsen H, Hui K, Barraud N, Filloux A
Mol. Microbiol. 2013 Aug;89(3):450-63
PubMed ID: 23750818
The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes.
He J, Baldini RL, Déziel E, Saucier M, Zhang Q, Liberati NT, Lee D, Urbach J, Goodman HM, Rahme LG
Proc Natl Acad Sci U S A 2004 Feb 24;101(8):2530-5
PubMed ID: 14983043