Pseudomonas aeruginosa PAO1, PA0059 (osmC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0059
Name
osmC
Replicon chromosome
Genomic location 73468 - 73923 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248749.1
GI 15595257
Affymetrix PA0059_osmC_at
Entrez 878070
GenBank AAG03449.1
INSDC AAG03449.1
NCBI Locus Tag PA0059
protein_id(GenBank) gb|AAG03449.1|AE004445_10|gnl|PseudoCAP|PA0059
TIGR NTL03PA00060
UniParc UPI00000C4F0C
UniProtKB Acc Q9I773
UniProtKB ID Q9I773_PSEAE
UniRef100 UniRef100_Q9I773
UniRef50 UniRef50_P0C0L2
UniRef90 UniRef90_Q9I773

Product

Feature Type CDS
Coding Frame 1
Product Name
osmotically inducible protein OsmC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.35
Kyte-Doolittle Hydrophobicity Value -0.131
Molecular Weight (kDa) 15.6
Isoelectric Point (pI) 6.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000058 (540 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0059
Search term: osmC

Human Homologs

References

Osmotic induction of gene osmC expression in Escherichia coli K12.
Gutierrez C, Devedjian JC
J Mol Biol 1991 Aug 20;220(4):959-73
PubMed ID: 1715407
Growth-phase-dependent expression of the osmotically inducible gene osmC of Escherichia coli K-12.
Gordia S, Gutierrez C
Mol. Microbiol. 1996 Feb;19(4):729-36
PubMed ID: 8820643
Interplay between global regulators of Escherichia coli: effect of RpoS, Lrp and H-NS on transcription of the gene osmC.
Bouvier J, Gordia S, Kampmann G, Lange R, Hengge-Aronis R, Gutierrez C
Mol. Microbiol. 1998 Jun;28(5):971-80
PubMed ID: 9663683