Pseudomonas aeruginosa PAO1, PA0216
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0216
|
| Name |
Synonym: madM |
| Replicon | chromosome |
| Genomic location | 243841 - 244605 (+ strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Comment | BIOLOG data shows growth on malonate. Annotation assigns PA0215 and PA0216 as having 71% and 81% homology with MadL and MadM from Malonomonas rubra. |
Cross-References
| RefSeq | NP_248907.1 |
| GI | 15595413 |
| Affymetrix | PA0216_at |
| Entrez | 879529 |
| GenBank | AAG03605.1 |
| INSDC | AAG03605.1 |
| NCBI Locus Tag | PA0216 |
| protein_id(GenBank) | gb|AAG03605.1|AE004459_9|gnl|PseudoCAP|PA0216 |
| TIGR | NTL03PA00217 |
| UniParc | UPI00000C4F9F |
| UniProtKB Acc | Q9I6S2 |
| UniProtKB ID | Q9I6S2_PSEAE |
| UniRef100 | UniRef100_W0YMD6 |
| UniRef50 | UniRef50_Q87V62 |
| UniRef90 | UniRef90_A6UY11 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
malonate transporter MadM
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 4.16 |
| Kyte-Doolittle Hydrophobicity Value | 1.045 |
| Molecular Weight (kDa) | 25.4 |
| Isoelectric Point (pI) | 9.32 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 30 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000215 (488 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0216
Search term: malonate transporter MadM
|
Human Homologs
References
|
Identification of an Na+-dependent malonate transporter of Malonomonas rubra and its dependence on two separate genes.
Schaffitzel C, Berg M, Dimroth P, Pos KM
J. Bacteriol. 1998 May;180(10):2689-93
PubMed ID: 9573154
|