Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0363
|
Name |
coaD
Synonym: kdtB |
Replicon | chromosome |
Genomic location | 406619 - 407098 (- strand) |
RefSeq | NP_249054.1 |
GI | 15595560 |
Affymetrix | PA0363_coaD_at |
Entrez | 879847 |
GenBank | AAG03752.1 |
INSDC | AAG03752.1 |
NCBI Locus Tag | PA0363 |
protein_id(GenBank) | gb|AAG03752.1|AE004474_4|gnl|PseudoCAP|PA0363 |
TIGR | NTL03PA00364 |
UniParc | UPI0000127CC2 |
UniProtKB Acc | Q9I6D1 |
UniProtKB ID | COAD_PSEAE |
UniRef100 | UniRef100_B7V2S6 |
UniRef50 | UniRef50_Q5ZY26 |
UniRef90 | UniRef90_B7V2S6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
phosphopantetheine adenylyltransferase
|
Synonyms |
PPAT |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 2.19 |
Kyte-Doolittle Hydrophobicity Value | -0.007 |
Molecular Weight (kDa) | 17.8 |
Isoelectric Point (pI) | 8.95 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5TS2 | TRANSFERASE | 10/27/16 | Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A | Pseudomonas aeruginosa (strain LESB58) | 2.3 | X-RAY DIFFRACTION | 100.0 |
4RUK | TRANSFERASE | 11/20/14 | crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with CoA and pyrophosphate from Pseudomonas aeruginosa | Pseudomonas aeruginosa 2192 | 2.2 | X-RAY DIFFRACTION | 100.0 |
3X1M | TRANSFERASE | 11/24/14 | Crystal structure of Phosphopantetheine adenylyltransferase/PPAT from Pseudomonas aeruginosa with CoA | Pseudomonas aeruginosa 2192 | 2.5 | X-RAY DIFFRACTION | 100.0 |
3X1K | TRANSFERASE | 11/20/14 | crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with AMP-PNP from Pseudomonas aerugonosa | Pseudomonas aeruginosa 2192 | 2.547 | X-RAY DIFFRACTION | 100.0 |
5X6F | TRANSFERASE | 02/21/17 | Crystal structure of Phosphopantetheine adenylyltransferase from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.593 | X-RAY DIFFRACTION | 100.0 |
3X1J | TRANSFERASE | 11/19/14 | Crystal Structure of Phosphopantetheine adenylyltransferase (PPAT/CoaD) with AcCoA from Pseudomonas aeruginosa | Pseudomonas aeruginosa 2192 | 2.334 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 578 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000354 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0363
Search term: coaD
Search term: phosphopantetheine adenylyltransferase
|
A gene coding for 3-deoxy-D-manno-octulosonic-acid transferase in Escherichia coli. Identification, mapping, cloning, and sequencing.
Clementz T, Raetz CR
J Biol Chem 1991 May 25;266(15):9687-96
PubMed ID: 2033061
|
Genetic analysis of the genes involved in synthesis of the lipopolysaccharide core in Escherichia coli K-12: three operons in the rfa locus.
Roncero C, Casadaban MJ
J Bacteriol 1992 May;174(10):3250-60
PubMed ID: 1577693
|
Purification and characterization of phosphopantetheine adenylyltransferase from Escherichia coli.
Geerlof A, Lewendon A, Shaw WV
J Biol Chem 1999 Sep 17;274(38):27105-11
PubMed ID: 10480925
|