Pseudomonas aeruginosa PAO1, PA2991 (sth)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2991
Name
sth
Replicon chromosome
Genomic location 3348838 - 3350232 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_251681.1
GI 15598187
Affymetrix PA2991_sth_at
Entrez 878679
GenBank AAG06379.1
INSDC AAG06379.1
NCBI Locus Tag PA2991
protein_id(GenBank) gb|AAG06379.1|AE004724_8|gnl|PseudoCAP|PA2991
TIGR NTL03PA02991
UniParc UPI0000165ECB
UniProtKB Acc P57112
UniProtKB ID STHA_PSEAE
UniRef100 UniRef100_B7UZU5
UniRef50 UniRef50_O05139
UniRef90 UniRef90_B7UZU5

Product

Feature Type CDS
Coding Frame 1
Product Name
soluble pyridine nucleotide transhydrogenase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.71
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 51.2
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 649 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002590 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2991
Search term: sth

Human Homologs

References

Cloning, sequence, and properties of the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens.
French CE, Boonstra B, Bufton KA, Bruce NC
J Bacteriol 1997 Apr;179(8):2761-5
PubMed ID: 9098078