Pseudomonas aeruginosa PAO1, PA3128

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3128
Name
Synonym: ygfF
Replicon chromosome
Genomic location 3510144 - 3510890 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251818.1
GI 15598324
Affymetrix PA3128_at
Entrez 882636
GenBank AAG06516.1
INSDC AAG06516.1
NCBI Locus Tag PA3128
protein_id(GenBank) gb|AAG06516.1|AE004737_2|gnl|PseudoCAP|PA3128
TIGR NTL03PA03128
UniParc UPI00000C591D
UniProtKB Acc Q9HZ96
UniProtKB ID Q9HZ96_PSEAE
UniRef100 UniRef100_A0A0C7CZH8
UniRef50 UniRef50_Q12GY8
UniRef90 UniRef90_A0A086BZR1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.30
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 26.2
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
8BCJ UNKNOWN FUNCTION 10/16/22 Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1 in complex with NADP+ Pseudomonas aeruginosa PAO1 1.15 X-RAY DIFFRACTION 100.0
8BCI UNKNOWN FUNCTION 10/16/22 Crystal structure of short-chain dehydrogenase PA3128 from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 1.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002470 (529 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3128

Human Homologs

Ensembl 110, assembly GRCh38.p14
carbonyl reductase 4 [Source:HGNC Symbol;Acc:HGNC:25891]
E-value: 3.9e-29
Percent Identity: 38.2

References

No references are associated with this feature.