Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3225
|
Name |
|
Replicon | chromosome |
Genomic location | 3612559 - 3613488 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | PA3225 promotes antibiotic susceptibility by acting as a transcriptional repressor of the MexAB-OprM efflux pump as well as of putative antibiotic resistance determinants encoded by PA1210, PA2864, and PA3228. |
RefSeq | NP_251915.1 |
GI | 15598421 |
Affymetrix | PA3225_at |
DNASU | PaCD00007419 |
Entrez | 882530 |
GenBank | AAG06613.1 |
INSDC | AAG06613.1 |
NCBI Locus Tag | PA3225 |
protein_id(GenBank) | gb|AAG06613.1|AE004745_10|gnl|PseudoCAP|PA3225 |
TIGR | NTL03PA03225 |
UniParc | UPI00000C595E |
UniProtKB Acc | Q9HZ15 |
UniProtKB ID | Q9HZ15_PSEAE |
UniRef100 | UniRef100_W0YWR1 |
UniRef50 | UniRef50_Q4KGG2 |
UniRef90 | UniRef90_A6V2J7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
transcriptional regulator
|
Synonyms |
probable transcriptional regulator |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 1.62 |
Kyte-Doolittle Hydrophobicity Value | -0.160 |
Molecular Weight (kDa) | 34.1 |
Isoelectric Point (pI) | 7.44 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 402 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002388 (533 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3225
Search term: transcriptional regulator
|
PA3225 Is a Transcriptional Repressor of Antibiotic Resistance Mechanisms in Pseudomonas aeruginosa.
Hall CW, Zhang L, Mah TF
Antimicrob Agents Chemother 2017 Aug;61(8)
PubMed ID: 28584154
|