Pseudomonas aeruginosa PAO1, PA3334 (acp3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3334
Name
acp3
Replicon chromosome
Genomic location 3743700 - 3743939 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Comment

Cross-References

RefSeq NP_252024.1
GI 15598530
Affymetrix PA3334_at
Entrez 882499
GenBank AAG06722.1
INSDC AAG06722.1
NCBI Locus Tag PA3334
protein_id(GenBank) gb|AAG06722.1|AE004755_9|gnl|PseudoCAP|PA3334
TIGR NTL03PA03334
UniParc UPI00000C59BC
UniProtKB Acc Q9HYR1
UniProtKB ID Q9HYR1_PSEAE
UniRef100 UniRef100_W0YU34
UniRef50 UniRef50_W0YU34
UniRef90 UniRef90_W0YU34

Product

Feature Type CDS
Coding Frame 1
Product Name
Acp3
Product Name Confidence: Class 1
Synonyms probable acyl carrier protein
Evidence for Translation
Charge (pH 7) -10.52
Kyte-Doolittle Hydrophobicity Value -0.159
Molecular Weight (kDa) 8.9
Isoelectric Point (pI) 4.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2LTE TRANSFERASE 05/18/12 Solution NMR structure of the specialized acyl carrier protein PA3334 (apo) from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaT415 Pseudomonas aeruginosa NOT SOLUTION NMR 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002294 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3334
Search term: acp3
Search term: Acp3

Human Homologs

References

Refinement of the NMR structures for acyl carrier protein with scalar coupling data.
Kim Y, Prestegard JH
Proteins 1990;8(4):377-85
PubMed ID: 2091027
Domains of Escherichia coli acyl carrier protein important for membrane-derived-oligosaccharide biosynthesis.
Tang L, Weissborn AC, Kennedy EP
J Bacteriol 1997 Jun;179(11):3697-705
PubMed ID: 9171419
Acyl Carrier Protein 3 Is Involved in Oxidative Stress Response in Pseudomonas aeruginosa.
Chen W, Wang B, Gruber JD, Zhang YM, Davies C
Front Microbiol 2018;9:2244
PubMed ID: 30294316