Pseudomonas aeruginosa PAO1, PA3376

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3376
Name
Synonym: phnK
Replicon chromosome
Genomic location 3783599 - 3784414 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252066.1
GI 15598572
Affymetrix PA3376_at
Entrez 879948
GenBank AAG06764.1
INSDC AAG06764.1
NCBI Locus Tag PA3376
protein_id(GenBank) gb|AAG06764.1|AE004759_11|gnl|PseudoCAP|PA3376
TIGR NTL03PA03376
UniParc UPI00000C59DD
UniProtKB Acc Q9HYM5
UniProtKB ID Q9HYM5_PSEAE
UniRef100 UniRef100_A0A077JSS4
UniRef50 UniRef50_Q30W20
UniRef90 UniRef90_A6V252

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -7.36
Kyte-Doolittle Hydrophobicity Value -0.150
Molecular Weight (kDa) 29.9
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002251 (340 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3376

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]
E-value: 9.4e-13
Percent Identity: 23.9
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]
E-value: 9.4e-13
Percent Identity: 23.9
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]
E-value: 9.4e-13
Percent Identity: 23.9

References

Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B.
Chen CM, Ye QZ, Zhu ZM, Wanner BL, Walsh CT
J Biol Chem 1990 Mar 15;265(8):4461-71
PubMed ID: 2155230