Pseudomonas aeruginosa PAO1, PA3387 (rhlG)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA3387
Name	rhlG
Replicon	chromosome
Genomic location	3792290 - 3793060 (+ strand)
Transposon Mutants	2 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_252077.1
GI	15598583
Affymetrix	PA3387_rhlG_at
Entrez	880033
GenBank	AAG06775.1
INSDC	AAG06775.1
NCBI Locus Tag	PA3387
protein_id(GenBank)	gb|AAG06775.1|AE004760_3|gnl|PseudoCAP|PA3387
TIGR	NTL03PA03387
UniParc	UPI000013387C
UniProtKB Acc	Q9RPT1
UniProtKB ID	RHLG_PSEAE
UniRef100	UniRef100_Q9RPT1
UniRef50	UniRef50_Q9RPT1
UniRef90	UniRef90_Q9RPT1

Product

Feature Type	CDS
Coding Frame	1
Product Name	beta-ketoacyl reductase Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	0.07
Kyte-Doolittle Hydrophobicity Value	0.141
Molecular Weight (kDa)	26.8
Isoelectric Point (pI)	7.03

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
2B4Q	OXIDOREDUCTASE	09/26/05	Pseudomonas aeruginosa RhlG/NADP active-site complex	Pseudomonas aeruginosa	2.3	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002241 (350 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA3387 Search term: rhlG Search term: beta-ketoacyl reductase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000334113 dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399] E-value: 3.2e-10 Percent Identity: 28.8
Ensembl 110, assembly GRCh38.p14	ENSP00000518604 dehydrogenase/reductase X-linked [Source:HGNC Symbol;Acc:HGNC:18399] E-value: 3.2e-10 Percent Identity: 28.8

References