Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3418
|
Name |
ldh
|
Replicon | chromosome |
Genomic location | 3824748 - 3825773 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252108.1 |
GI | 15598614 |
Affymetrix | PA3418_ldh_at |
DNASU | PaCD00007502 |
Entrez | 879877 |
GenBank | AAG06806.1 |
INSDC | AAG06806.1 |
NCBI Locus Tag | PA3418 |
protein_id(GenBank) | gb|AAG06806.1|AE004763_1|gnl|PseudoCAP|PA3418 |
TIGR | NTL03PA03418 |
UniParc | UPI00000C5A00 |
UniProtKB Acc | Q9HYI7 |
UniProtKB ID | Q9HYI7_PSEAE |
UniRef100 | UniRef100_Q9HYI7 |
UniRef50 | UniRef50_S6AZW7 |
UniRef90 | UniRef90_Q9HYI7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
leucine dehydrogenase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -7.30 |
Kyte-Doolittle Hydrophobicity Value | 0.059 |
Molecular Weight (kDa) | 35.6 |
Isoelectric Point (pI) | 5.91 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
7VID | OXIDOREDUCTASE | 09/26/21 | The crystal structure of L-leucine dehydrogenase from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 2.5 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 344 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002212 (502 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3418
Search term: ldh
Search term: leucine dehydrogenase
|
Gene cloning and sequence determination of leucine dehydrogenase from Bacillus stearothermophilus and structural comparison with other NAD(P)+-dependent dehydrogenases.
Nagata S, Tanizawa K, Esaki N, Sakamoto Y, Ohshima T, Tanaka H, Soda K
Biochemistry 1988 Dec 13;27(25):9056-62
PubMed ID: 3069133
|
Leucine dehydrogenase from Bacillus stearothermophilus: identification of active-site lysine by modification with pyridoxal phosphate.
Matsuyama T, Soda K, Fukui T, Tanizawa K
J Biochem 1992 Aug;112(2):258-65
PubMed ID: 1400267
|