Pseudomonas aeruginosa PAO1, PA3436

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3436
Name
Replicon chromosome
Genomic location 3844385 - 3844942 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252126.1
GI 15598632
Affymetrix PA3436_at
DNASU PaCD00007511
Entrez 879041
GenBank AAG06824.1
INSDC AAG06824.1
NCBI Locus Tag PA3436
protein_id(GenBank) gb|AAG06824.1|AE004764_10|gnl|PseudoCAP|PA3436
TIGR NTL03PA03436
UniParc UPI00000C5A0E
UniProtKB Acc Q9HYH0
UniProtKB ID Q9HYH0_PSEAE
UniRef100 UniRef100_Q9HYH0
UniRef50 UniRef50_A4XXH4
UniRef90 UniRef90_W0YXF5

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.19
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 20.6
Isoelectric Point (pI) 9.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 73 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002200 (498 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3436

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
P-type ATPase from the cyanobacterium Synechococcus 7942 related to the human Menkes and Wilson disease gene products.
Phung LT, Ajlani G, Haselkorn R
Proc Natl Acad Sci U S A 1994 Sep 27;91(20):9651-4
PubMed ID: 7937823