Pseudomonas aeruginosa PAO1, PA3494

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3494
Name
Synonym: rnfE
Replicon chromosome
Genomic location 3912410 - 3913132 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252184.1
GI 15598690
Affymetrix PA3494_at
DNASU PaCD00007535
Entrez 879980
GenBank AAG06882.1
INSDC AAG06882.1
NCBI Locus Tag PA3494
protein_id(GenBank) gb|AAG06882.1|AE004770_7|gnl|PseudoCAP|PA3494
TIGR NTL03PA03494
UniParc UPI00001343A4
UniProtKB Acc Q9HYB5
UniProtKB ID ETCE_PSEAE
UniRef100 UniRef100_Q9HYB5
UniRef50 UniRef50_Q8EE76
UniRef90 UniRef90_Q02QY3

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 2.11
Kyte-Doolittle Hydrophobicity Value 0.645
Molecular Weight (kDa) 25.8
Isoelectric Point (pI) 8.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 226 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002150 (349 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3494

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM
Science 1995 Jul 28;269(5223):496-512
PubMed ID: 7542800
Overexpression in Escherichia coli of the rnf genes from Rhodobacter capsulatus--characterization of two membrane-bound iron-sulfur proteins.
Jouanneau Y, Jeong HS, Hugo N, Meyer C, Willison JC
Eur J Biochem 1998 Jan 15;251(1-2):54-64
PubMed ID: 9492268