Pseudomonas aeruginosa PAO1, PA3758

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3758
Name
Synonym: nagA
Replicon chromosome
Genomic location 4208168 - 4209259 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252447.1
GI 15598953
Affymetrix PA3758_at
DNASU PaCD00007639
Entrez 880471
GenBank AAG07145.1
INSDC AAG07145.1
NCBI Locus Tag PA3758
protein_id(GenBank) gb|AAG07145.1|AE004794_10|gnl|PseudoCAP|PA3758
TIGR NTL03PA03758
UniParc UPI00000C5AF8
UniProtKB Acc Q9HXN7
UniProtKB ID Q9HXN7_PSEAE
UniRef100 UniRef100_W0YVC9
UniRef50 UniRef50_Q02RN1
UniRef90 UniRef90_Q02RN1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable N-acetylglucosamine-6-phosphate deacetylase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.54
Kyte-Doolittle Hydrophobicity Value -0.009
Molecular Weight (kDa) 38.8
Isoelectric Point (pI) 6.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 341 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001924 (386 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3758

Human Homologs

References

Sequence of the nagBACD operon in Escherichia coli K12 and pattern of transcription within the nag regulon.
Plumbridge JA
Mol Microbiol 1989 Apr;3(4):505-15
PubMed ID: 2668691