Pseudomonas aeruginosa PAO1, PA3914 (moeA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3914
Name
moeA1
Replicon chromosome
Genomic location 4384022 - 4385245 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_252603.1
GI 15599109
Affymetrix PA3914_moeA1_at
Entrez 878989
GenBank AAG07301.1
INSDC AAG07301.1
NCBI Locus Tag PA3914
protein_id(GenBank) gb|AAG07301.1|AE004809_1|gnl|PseudoCAP|PA3914
TIGR NTL03PA03914
UniParc UPI00000C5B74
UniProtKB Acc Q9HX99
UniProtKB ID Q9HX99_PSEAE
UniRef100 UniRef100_Q9HX99
UniRef50 UniRef50_G0EZR9
UniRef90 UniRef90_Q9HX99

Product

Feature Type CDS
Coding Frame 1
Product Name
molybdenum cofactor biosynthetic protein A1
Product Name Confidence: Class 3
Synonyms molybdopterin biosynthetic protein MoeA
Evidence for Translation
Charge (pH 7) -2.99
Kyte-Doolittle Hydrophobicity Value 0.068
Molecular Weight (kDa) 43.2
Isoelectric Point (pI) 6.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 539 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001762 (887 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3914
Search term: moeA1

Human Homologs

References

Physiological and genetic analyses leading to identification of a biochemical role for the moeA (molybdate metabolism) gene product in Escherichia coli.
Hasona A, Ray RM, Shanmugam KT
J Bacteriol 1998 Mar;180(6):1466-72
PubMed ID: 9515915
Molybdate-dependent transcription of hyc and nar operons of Escherichia coli requires MoeA protein and ModE-molybdate.
Hasona A, Self WT, Ray RM, Shanmugam KT
FEMS Microbiol Lett 1998 Dec 1;169(1):111-6
PubMed ID: 9851041