Pseudomonas aeruginosa PAO1, PA3942 (tesB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3942
Name
tesB
Replicon chromosome
Genomic location 4419301 - 4420170 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252631.1
GI 15599137
Affymetrix PA3942_tesB_at
Entrez 878836
GenBank AAG07329.1
INSDC AAG07329.1
NCBI Locus Tag PA3942
protein_id(GenBank) gb|AAG07329.1|AE004812_4|gnl|PseudoCAP|PA3942
TIGR NTL03PA03942
UniParc UPI00000C5B8A
UniProtKB Acc Q9HX74
UniProtKB ID Q9HX74_PSEAE
UniRef100 UniRef100_W0YX96
UniRef50 UniRef50_C0QIT9
UniRef90 UniRef90_A6V0G6

Product

Feature Type CDS
Coding Frame 1
Product Name
acyl-CoA thioesterase II
Product Name Confidence: Class 2
Synonyms TesB
Evidence for Translation
Charge (pH 7) -6.59
Kyte-Doolittle Hydrophobicity Value -0.435
Molecular Weight (kDa) 32.9
Isoelectric Point (pI) 5.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 182 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001734 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3942
Search term: tesB

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919]
E-value: 1.1e-56
Percent Identity: 42.1

References

Cloning, sequencing, and characterization of Escherichia coli thioesterase II.
Naggert J, Narasimhan ML, DeVeaux L, Cho H, Randhawa ZI, Cronan JE Jr, Green BN, Smith S
J Biol Chem 1991 Jun 15;266(17):11044-50
PubMed ID: 1645722
The complete genome sequence of Escherichia coli K-12.
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
Science 1997 Sep 5;277(5331):1453-62
PubMed ID: 9278503