Pseudomonas aeruginosa PAO1, PA4055 (ribC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4055
Name
ribC
Synonym: ribB
Replicon chromosome
Genomic location 4535834 - 4536493 (- strand)

Cross-References

RefSeq NP_252744.1
GI 15599250
Affymetrix PA4055_ribC_at
DNASU PaCD00007773
Entrez 878915
GenBank AAG07442.1
INSDC AAG07442.1
NCBI Locus Tag PA4055
protein_id(GenBank) gb|AAG07442.1|AE004822_2|gnl|PseudoCAP|PA4055
TIGR NTL03PA04055
UniParc UPI00000C5BE2
UniProtKB Acc Q9HWX3
UniProtKB ID Q9HWX3_PSEAE
UniRef100 UniRef100_W0YY77
UniRef50 UniRef50_V6AA82
UniRef90 UniRef90_V6AA82

Product

Feature Type CDS
Coding Frame 1
Product Name
riboflavin synthase alpha chain
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.83
Kyte-Doolittle Hydrophobicity Value 0.019
Molecular Weight (kDa) 23.5
Isoelectric Point (pI) 6.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 568 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001629 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4055
Search term: ribC

Human Homologs

References

Riboflavin synthases of Bacillus subtilis. Purification and amino acid sequence of the alpha subunit.
Schott K, Kellermann J, Lottspeich F, Bacher A
J Biol Chem 1990 Mar 15;265(8):4204-9
PubMed ID: 2106516
Studies on the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution.
Ritsert K, Huber R, Turk D, Ladenstein R, Schmidt-Bäse K, Bacher A
J Mol Biol 1995 Oct 13;253(1):151-67
PubMed ID: 7473709