Pseudomonas aeruginosa PAO1, PA4083 (cupB4)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4083
Name
cupB4
Replicon chromosome
Genomic location 4564684 - 4565424 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_252772.1
GI 15599278
Affymetrix PA4083_at
DNASU PaCD00007785
Entrez 878709
GenBank AAG07470.1
INSDC AAG07470.1
NCBI Locus Tag PA4083
protein_id(GenBank) gb|AAG07470.1|AE004824_5|gnl|PseudoCAP|PA4083
TIGR NTL03PA04083
UniParc UPI00000C5BFD
UniProtKB Acc Q9HWU5
UniProtKB ID Q9HWU5_PSEAE
UniRef100 UniRef100_Q9HWU5
UniRef50 UniRef50_Q9HWU5
UniRef90 UniRef90_Q9HWU5

Product

Feature Type CDS
Coding Frame 1
Product Name
chaperone CupB4
Product Name Confidence: Class 2
Synonyms probable pili assembly chaperone
Evidence for Translation
Charge (pH 7) -2.31
Kyte-Doolittle Hydrophobicity Value 0.012
Molecular Weight (kDa) 26.4
Isoelectric Point (pI) 5.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 46 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000956 (1721 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4083
Search term: cupB4
Search term: chaperone CupB4

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295