Pseudomonas aeruginosa PAO1, PA4142

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4142
Name
Replicon chromosome
Genomic location 4632873 - 4634129 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252831.1
GI 15599337
Affymetrix PA4142_at
Entrez 880112
GenBank AAG07529.1
INSDC AAG07529.1
NCBI Locus Tag PA4142
protein_id(GenBank) gb|AAG07529.1|AE004831_1|gnl|PseudoCAP|PA4142
TIGR NTL03PA04142
UniParc UPI00000C5C33
UniProtKB Acc Q9HWN9
UniProtKB ID Q9HWN9_PSEAE
UniRef100 UniRef100_A0A072ZEY0
UniRef50 UniRef50_G0AAK2
UniRef90 UniRef90_A6UZU8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable secretion protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 3.73
Kyte-Doolittle Hydrophobicity Value -0.297
Molecular Weight (kDa) 46.1
Isoelectric Point (pI) 9.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 255 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001557 (323 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4142

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Genetic analysis of an MDR-like export system: the secretion of colicin V.
Gilson L, Mahanty HK, Kolter R
EMBO J 1990 Dec;9(12):3875-84
PubMed ID: 2249654