Pseudomonas aeruginosa PAO1, PA4156 (fvbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4156
Name
fvbA
Replicon chromosome
Genomic location 4650374 - 4652458 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252845.1
GI 15599351
Affymetrix PA4156_at
Entrez 880160
GenBank AAG07543.1
INSDC AAG07543.1
NCBI Locus Tag PA4156
protein_id(GenBank) gb|AAG07543.1|AE004832_3|gnl|PseudoCAP|PA4156
TIGR NTL03PA04156
UniParc UPI00000C5C41
UniProtKB Acc Q9HWM5
UniProtKB ID Q9HWM5_PSEAE
UniRef100 UniRef100_Q9HWM5
UniRef50 UniRef50_Q9HWM5
UniRef90 UniRef90_Q9HWM5

Product

Feature Type CDS
Coding Frame 1
Product Name
FvbA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.81
Kyte-Doolittle Hydrophobicity Value -0.516
Molecular Weight (kDa) 76.8
Isoelectric Point (pI) 5.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 198 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001545 (323 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4156
Search term: fvbA
Search term: FvbA

Human Homologs

References

Cloning, sequencing, and transcriptional regulation of viuA, the gene encoding the ferric vibriobactin receptor of Vibrio cholerae.
Butterton JR, Stoebner JA, Payne SM, Calderwood SB
J Bacteriol 1992 Jun;174(11):3729-38
PubMed ID: 1317381
FvbA is required for vibriobactin utilization in Pseudomonas aeruginosa.
Elias S, Degtyar E, Banin E
Microbiology (Reading) 2011 Jul;157(Pt 7):2172-2180
PubMed ID: 21546589