Pseudomonas aeruginosa PAO1, PA4504 (dppC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4504
Name
dppC
Replicon chromosome
Genomic location 5043090 - 5044001 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253194.1
GI 15599700
Affymetrix PA4504_at
Entrez 881081
GenBank AAG07892.1
INSDC AAG07892.1
NCBI Locus Tag PA4504
protein_id(GenBank) gb|AAG07892.1|AE004864_4|gnl|PseudoCAP|PA4504
TIGR NTL03PA04505
UniParc UPI00000C5D40
UniProtKB Acc Q9HVR7
UniProtKB ID Q9HVR7_PSEAE
UniRef100 UniRef100_Z2DN44
UniRef50 UniRef50_P0AEG3
UniRef90 UniRef90_Q02GT7

Product

Feature Type CDS
Coding Frame 1
Product Name
dipeptide ABC transporter permease DppC
Product Name Confidence: Class 1
Synonyms probable permease of ABC transporter
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.38
Kyte-Doolittle Hydrophobicity Value 0.739
Molecular Weight (kDa) 32.4
Isoelectric Point (pI) 8.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004091 (513 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4504
Search term: dppC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D, Lafon C, Braun Y, Köhler T, Page MG, Mourez M, Weingart H
PLoS One 2014;9(10):e111311
PubMed ID: 25338022