Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4528
|
Name |
pilD
Synonym: xcpA |
Replicon | chromosome |
Genomic location | 5072695 - 5073567 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_253218.1 |
GI | 15599724 |
Affymetrix | PA4528_pilD_at |
Entrez | 877861 |
GenBank | AAG07916.1 |
NCBI Locus Tag | PA4528 |
protein_id(GenBank) | gb|AAG07916.1|AE004867_2|gnl|PseudoCAP|PA4528 |
TIGR | NTL03PA04529 |
UniProtKB Acc | P22610 |
UniProtKB ID | LEP4_PSEAE |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type 4 prepilin peptidase PilD
|
Synonyms |
type 4 fimbrial biogenesis protein PilD |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 2.27 |
Kyte-Doolittle Hydrophobicity Value | 0.637 |
Molecular Weight (kDa) | 31.9 |
Isoelectric Point (pI) | 7.90 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0082 |
Category | Type IV pili biosynthesis |
Evidence |
|
Host Organism | |
Notes | |
Reference | |
Source 2 | |
Database | Victors : 4208 |
Category | Type IV pili biosynthesis |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | |
Infection model | Rat agar bead model of chronic lung infection |
Reference | 14641575 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 366 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004109 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4528
Search term: pilD
Search term: type 4 prepilin peptidase PilD
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Products of three accessory genes, pilB, pilC, and pilD, are required for biogenesis of Pseudomonas aeruginosa pili.
Nunn D, Bergman S, Lory S
J Bacteriol 1990 Jun;172(6):2911-9
PubMed ID: 1971619
|
Protein secretion in Pseudomonas aeruginosa: the xcpA gene encodes an integral inner membrane protein homologous to Klebsiella pneumoniae secretion function protein PulO.
Bally M, Ball G, Badere A, Lazdunski A
J Bacteriol 1991 Jan;173(2):479-86
PubMed ID: 1898929
|
Protein secretion in Pseudomonas aeruginosa: characterization of seven xcp genes and processing of secretory apparatus components by prepilin peptidase.
Bally M, Filloux A, Akrim M, Ball G, Lazdunski A, Tommassen J
Mol Microbiol 1992 May;6(9):1121-31
PubMed ID: 1588814
|
Type II protein secretion by Pseudomonas aeruginosa: genetic suppression of a conditional mutation in the pilin-like component XcpT by the cytoplasmic component XcpR.
Kagami Y, Ratliff M, Surber M, Martinez A, Nunn DN
Mol Microbiol 1998 Jan;27(1):221-33
PubMed ID: 9466269
|