Pseudomonas aeruginosa PAO1, PA4982

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4982
Name
Replicon chromosome
Genomic location 5595279 - 5598275 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253669
GI 15600175
Affymetrix PA4982_at
Entrez 880340
GenBank AAG08367.1
NCBI Locus Tag PA4982
protein_id(GenBank) gb|AAG08367.1|AE004911_2|gnl|PseudoCAP|PA4982
TIGR NTL03PA04983
UniProtKB Acc Q9HUI3
UniProtKB ID Q9HUI3_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms probable histidine kinase
Evidence for Translation
Charge (pH 7) 46.40
Kyte-Doolittle Hydrophobicity Value -0.318
Molecular Weight (kDa) 109.1
Isoelectric Point (pI) 11.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 620 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004594 (357 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4982

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of genes encoding dimethyl sulfoxide reductase of Rhodobacter sphaeroides 2.4.1T: an essential metabolic gene function encoded on chromosome II.
Mouncey NJ, Choudhary M, Kaplan S
J Bacteriol 1997 Dec;179(24):7617-24
PubMed ID: 9401017