Pseudomonas aeruginosa PAO1, PA0115
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0115
|
| Name |
Synonym: elaA |
| Replicon | chromosome |
| Genomic location | 135934 - 136386 (- strand) |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248805.1 |
| GI | 15595313 |
| Affymetrix | PA0115_at |
| DNASU | PaCD00006050 |
| Entrez | 880693 |
| GenBank | AAG03505.1 |
| INSDC | AAG03505.1 |
| NCBI Locus Tag | PA0115 |
| protein_id(GenBank) | gb|AAG03505.1|AE004449_14|gnl|PseudoCAP|PA0115 |
| TIGR | NTL03PA00116 |
| UniParc | UPI00000C4F44 |
| UniProtKB Acc | Q9I717 |
| UniProtKB ID | Q9I717_PSEAE |
| UniRef100 | UniRef100_W0YKZ0 |
| UniRef50 | UniRef50_P0AEH3 |
| UniRef90 | UniRef90_A6UXQ1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Acyl-CoA N-acyltransferase
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -3.15 |
| Kyte-Doolittle Hydrophobicity Value | -0.115 |
| Molecular Weight (kDa) | 17.1 |
| Isoelectric Point (pI) | 6.30 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 1XEB | TRANSFERASE | 09/09/04 | Crystal Structure of an Acyl-CoA N-acyltransferase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.35 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 262 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000113 (511 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0115
Search term: Acyl-CoA N-acyltransferase
|
Human Homologs
References
|
Predicting drug targets by homology modelling of Pseudomonas aeruginosa proteins of unknown function.
Babic N, Kovacic F
PLoS One 2021;16(10):e0258385
PubMed ID: 34648550
|