Pseudomonas aeruginosa PAO1, PA0224 (ergA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0224
Name
ergA
Replicon chromosome
Genomic location 253854 - 254636 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_248915.1
GI 15595421
Affymetrix PA0224_at
DNASU PaCD00006100
Entrez 878177
GenBank AAG03613.1
INSDC AAG03613.1
NCBI Locus Tag PA0224
protein_id(GenBank) gb|AAG03613.1|AE004460_6|gnl|PseudoCAP|PA0224
TIGR NTL03PA00225
UniParc UPI00000C4FA7
UniProtKB Acc Q9I6R4
UniProtKB ID Q9I6R4_PSEAE
UniRef100 UniRef100_W0YL01
UniRef50 UniRef50_L7V4C9
UniRef90 UniRef90_A6UY21

Product

Feature Type CDS
Coding Frame 1
Product Name
ErgA
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -4.09
Kyte-Doolittle Hydrophobicity Value -0.075
Molecular Weight (kDa) 28.4
Isoelectric Point (pI) 6.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 320 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000223 (926 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0224
Search term: ergA
Search term: ErgA

Human Homologs

References

Species-specific recruitment of transcription factors dictates toxin expression.
Trouillon J, Sentausa E, Ragno M, Robert-Genthon M, Lory S, Attrée I, Elsen S
Nucleic Acids Res 2020 Mar 18;48(5):2388-2400
PubMed ID: 31925438