Pseudomonas aeruginosa PAO1, PA0231 (pcaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0231
Name
pcaD
Replicon chromosome
Genomic location 261179 - 261970 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248922.1
GI 15595428
Affymetrix PA0231_pcaD_at
DNASU PaCD00006103
Entrez 882150
GenBank AAG03620.1
INSDC AAG03620.1
NCBI Locus Tag PA0231
protein_id(GenBank) gb|AAG03620.1|AE004461_3|gnl|PseudoCAP|PA0231
TIGR NTL03PA00232
UniParc UPI00000C4FAE
UniProtKB Acc Q9I6Q7
UniProtKB ID Q9I6Q7_PSEAE
UniRef100 UniRef100_W0YMF0
UniRef50 UniRef50_Q0K0V4
UniRef90 UniRef90_A6UY28

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-ketoadipate enol-lactone hydrolase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.65
Kyte-Doolittle Hydrophobicity Value 0.155
Molecular Weight (kDa) 28.0
Isoelectric Point (pI) 5.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 414 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000230 (992 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0231
Search term: pcaD

Human Homologs

References

Characterization of Bradyrhizobium japonicum pcaBDC genes involved in 4-hydroxybenzoate degradation.
Lorite MJ, Sanjuan J, Velasco L, Olivares J, Bedmar EJ
Biochim Biophys Acta 1998 May 11;1397(3):257-61
PubMed ID: 9582432