Pseudomonas aeruginosa PAO1, PA0036 (trpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
3127651 Reviewed by curator
Molecular Function GO:0004834 tryptophan synthase activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
3127651 Reviewed by curator
Biological Process GO:0000162 tryptophan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
3127651 Reviewed by curator
Biological Process GO:0000162 tryptophan biosynthetic process
NAS
Non-traceable Author Statement
ECO:0000303
non-traceable author statement used in manual assertion
3127651 Reviewed by curator
Molecular Function GO:0016833 oxo-acid-lyase activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0000162 tryptophan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00133
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00168
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00168
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis ECO:0000037
not_recorded
PseudoCyc COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc ALL-CHORISMATE-PWY superpathway of chorismate metabolism 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
PseudoCyc TRPSYN-PWY L-tryptophan biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit IPR006654 Tryptophan synthase, beta chain 12 395 0.0
PIRSF PIRSF001413 IPR023026 Tryptophan synthase beta chain/beta chain-like 4 402 0.0
Gene3D G3DSA:3.40.50.1100 59 389 0.0
Hamap MF_00133 Tryptophan synthase beta chain [trpB]. IPR023026 Tryptophan synthase beta chain/beta chain-like 7 396 52.811
CDD cd06446 Trp-synth_B IPR006654 Tryptophan synthase, beta chain 32 392 0.0
Gene3D G3DSA:3.40.50.1100 15 211 0.0
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Pyridoxal-phosphate dependent enzyme 58 383 3.0E-46
SUPERFAMILY SSF53686 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme 8 394 0.0
ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. IPR006653 Tryptophan synthase, beta chain, conserved site 86 100 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.