Pseudomonas aeruginosa PAO1, PA0075 (pppA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0050709 negative regulation of protein secretion
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
17558395 Reviewed by curator
Molecular Function GO:0004722 protein serine/threonine phosphatase activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
17558395 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00143
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Putative enzymes Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03070 Bacterial secretion system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSiteProfiles PS51746 PPM-type phosphatase domain profile. IPR001932 PPM-type phosphatase domain 8 241 24.844
SMART SM00332 IPR001932 PPM-type phosphatase domain 6 239 4.6E-25
CDD cd00143 PP2Cc IPR001932 PPM-type phosphatase domain 10 240 1.86154E-53
SMART SM00331 IPR001932 PPM-type phosphatase domain 15 241 1.1E-27
SUPERFAMILY SSF81606 IPR036457 PPM-type phosphatase domain superfamily 9 240 2.75E-58
Gene3D G3DSA:3.60.40.10 IPR036457 PPM-type phosphatase domain superfamily 4 241 9.3E-55
Pfam PF13672 Protein phosphatase 2C 21 207 1.4E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.