Pseudomonas aeruginosa PAK, PAK_05274 (pmrB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0071236	cellular response to antibiotic	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	14702327	Reviewed by curator
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	293	461	1.15E-37
FunFam	G3DSA:1.10.287.130:FF:000035	Two-component sensor histidine kinase	-	-	190	303	1.9E-36
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	352	458	2.5E-21
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	240	303	1.2E-9
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	385	399	7.8E-12
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	418	436	7.8E-12
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	239	304	2.6E-11
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	443	456	7.8E-12
Coils	Coil	Coil	-	-	223	243	-
Gene3D	G3DSA:1.10.287.130	-	-	-	190	304	1.9E-16
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	455	477	-
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	237	300	4.95906E-12
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	222	303	1.2E-14
PANTHER	PTHR45436	SENSOR HISTIDINE KINASE YKOH	-	-	3	461	4.0E-91
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	348	459	1.2E-32
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	307	458	3.4E-36
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	403	413	7.8E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.