Pseudomonas aeruginosa PAO1, PA0143 (nuh)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008477 purine nucleosidase activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
15995202 Reviewed by curator
Biological Process GO:0009117 nucleotide metabolic process
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Biological Process GO:0006163 purine nucleotide metabolic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
15995202 Reviewed by curator
Molecular Function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01247
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00760 Nicotinate and nicotinamide metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain 41 340 1.4E-87
CDD cd02651 nuc_hydro_IU_UC_XIUA 42 346 2.9214E-148
ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site 45 55 -
Gene3D G3DSA:3.90.245.10 IPR036452 Ribonucleoside hydrolase-like 30 349 1.6E-104
SUPERFAMILY SSF53590 IPR036452 Ribonucleoside hydrolase-like 39 348 9.81E-98

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.