Pseudomonas aeruginosa PAO1, PA0402 (pyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006531 aspartate metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009117 nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006522 alanine metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004355 glutamate synthase (NADPH) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006220 pyrimidine nucleotide metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0016597 amino acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004070 aspartate carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016743 carboxyl- or carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006520 cellular amino acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53671
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Pyrimidine metabolism ECO:0000037
not_recorded
PseudoCyc PWY-5686 UMP biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Alanine and Aspartate metabolism ECO:0000037
not_recorded
PseudoCyc PRPP-PWY superpathway of histidine, purine, and pyrimidine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR45753 ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL - - 14 319 4.9E-65
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 284 307 7.7E-18
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 149 166 3.4E-31
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 150 161 7.7E-18
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 64 83 7.7E-18
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 92 101 3.4E-31
Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 170 317 1.9E-23
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 19 315 5.6E-84
Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. IPR002082 Aspartate carbamoyltransferase 17 321 41.801838
FunFam G3DSA:3.40.50.1370:FF:000007 Aspartate carbamoyltransferase - - 153 306 1.6E-68
NCBIfam TIGR00670 JCVI: aspartate carbamoyltransferase IPR002082 Aspartate carbamoyltransferase 18 319 1.8E-90
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 54 76 3.4E-31
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 300 314 3.4E-31
Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 18 162 2.8E-41
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 276 281 3.4E-31
SUPERFAMILY SSF53671 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 17 321 3.8E-95
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 272 281 7.7E-18
FunFam G3DSA:3.40.50.1370:FF:000006 Aspartate carbamoyltransferase - - 19 152 7.0E-73
PRINTS PR00101 Aspartate carbamoyltransferase signature - - 235 244 3.4E-31
Gene3D G3DSA:3.40.50.1370 Aspartate/ornithine carbamoyltransferase IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 150 306 5.6E-84

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.